Don't know where the 100 deaths per million estimate was found but the latest estimates from the CDC (as of March 9, 2021) provides estimates of 150 to 1,700 per million for individuals ages 18 to 49 based on the Ro (contagion rate) which varies from 2 to 4, as we know the new variants appear to be more infectious. (see the attached table from
https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios.htm
They also list the following most common co-morbidities:
1) Influenza and pneumonia 45.8%
2) Hypertension 19.8%
3) Diabetes 16%
4) Dementia including Alzheimer's 13.5%
5) Sepsis 9.6%
note that adds to more than 100% because patients can have more than 1 co-morbidity.
from:
https://www.cdc.gov/nchs/covid19/mortality-overview.htm
Actual risk of a blood clot event (not fatality) associated with the astrazeneca vaccine is estimated at 4 to 6 per million:
from:
https://www.hamiltonhealthsciences.ca/share/blood-clot-astrazeneca-vaccine-safety/
As of May 3, 2021, the CDC states that the rate of reported deaths after getting any covid vaccine in the US is 0.0017%. All deaths after a vaccine are reported even if the death was likely not caused by the vaccine (ie the result of an accident or previously known medical condition)
[quote}CDC uses the Vaccine Adverse Event Reporting System (VAERS) to closely monitor reports of death following COVID-19 vaccination.
- FDA requires healthcare providers to report any death after COVID-19 vaccination to VAERS.
- Reports to VAERS of death following vaccination do not necessarily mean the vaccine caused the death.
- CDC follows up on any report of death to request additional information to learn more about what occurred and to determine whether the death was a result of the vaccine or was unrelated.
- CDC, FDA, and other federal agencies will continue to monitor the safety of COVID-19 vaccines.
Over 245 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through May 3, 2021. During this time, VAERS received 4,178 reports of death (0.0017%) among people who received a COVID-19 vaccine. CDC and FDA physicians review each case report of death as soon as notified and CDC requests medical records to further assess reports
. A review of available clinical information, including death certificates, autopsy, and medical records has not established a causal link to COVID-19 vaccines. However, recent reports indicate a plausible causal relationship between the J&J/Janssen COVID-19 Vaccine and a rare and serious adverse event—blood clots with low platelets—which has caused deaths. Get the latest safety information on the J&J/Janssen vaccine. CDC and FDA will continue to investigate reports of adverse events, including deaths, reported to VAERS.