All Things COVID-19

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OldBlackDog said:
www.healthline.com

Can You Get COVID-19 Twice in a Month? Reinfections and Rebounds

Learn how soon and how often reinfections with SARS-CoV-2, the virus that causes COVID-19, can occur.
www.healthline.com www.healthline.com
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I don't doubt that this is true (although I admit that I only skimmed the article and am relying on a couple of conversations with doctor friends working on the problem in the states) but I believe that the T-cells residing in bone marrow etc are expected to retain enough of an imprint of the virus that they will still mount a good immune response if the body is not totally overwhelmed with massive viral load in the initial exposure.

I think some of the evidence for this is the seeming cross-immunity a fairly large percentage of the population has against this coronavirus, as a result of past exposures to other coronaviruses. I know (not well, but enough to chat with from time to time) an infectious disease specialist and asked him about this recently and I remember him saying that the broader immunity from coronavirus exposure almost certainly exists but I can't remember the details of the mechanism, because I'm not a doctor myself and most of what he said went over my head.

But I believe the vaccine - or maybe it was the immune response to the vaccine, I can't remember the conversation in that much detail - will give the T-cells enough of a look at the virus that although your antibodies will only last a few months, your body should still recognize the threat and attack it quickly for a number of years and I THINK the number of years he mentioned was ten, but I can't swear to it.

Anyway I realize this is third-hand info so everyone is free to ignore it but that's why I personally think that the vaccines should make a fairly big impact on this and should help us for longer than the antibodies last.

But I'm not a doctor and I huffed a LOT of glue today, so if you want more detail I'm afraid you're on your own.
 
cracked_ribs said:
I don't doubt that this is true (although I admit that I only skimmed the article and am relying on a couple of conversations with doctor friends working on the problem in the states) but I believe that the T-cells residing in bone marrow etc are expected to retain enough of an imprint of the virus that they will still mount a good immune response if the body is not totally overwhelmed with massive viral load in the initial exposure.

I think some of the evidence for this is the seeming cross-immunity a fairly large percentage of the population has against this coronavirus, as a result of past exposures to other coronaviruses. I know (not well, but enough to chat with from time to time) an infectious disease specialist and asked him about this recently and I remember him saying that the broader immunity from coronavirus exposure almost certainly exists but I can't remember the details of the mechanism, because I'm not a doctor myself and most of what he said went over my head.

But I believe the vaccine - or maybe it was the immune response to the vaccine, I can't remember the conversation in that much detail - will give the T-cells enough of a look at the virus that although your antibodies will only last a few months, your body should still recognize the threat and attack it quickly for a number of years and I THINK the number of years he mentioned was ten, but I can't swear to it.

Anyway I realize this is third-hand info so everyone is free to ignore it but that's why I personally think that the vaccines should make a fairly big impact on this and should help us for longer than the antibodies last.

But I'm not a doctor and I huffed a LOT of glue today, so if you want more detail I'm afraid you're on your own.
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That’s basically what a virologist that was a regular client told me about how the vaccine worked. Apparently this technology has been in fine tune mode since 2012
 
Fish_whistle_express said:
I’m a RN and will get the vaccine, as I want to decrease any risk of transmitting to my family and ageing parents. I also have a $3500 flight credit I would like to use and if the vaccine means I can travel to see family it’s a double win. I would prefer I was given a choice of vaccine or at least hear why were getting one vs the other. But it will likely be whatever is available.
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I wonder if after being vaccinated can one still carry and pass on the virus? I’m concerned that as soon as people get vaccinated it will be “yahoo, I don’t have to wear a mask and can get back to normal”. Meanwhile, at least at the beginning, the majority of the country will still be waiting to be vaccinated and susceptible to contacting the virus. Personally I can’t see the rules being relaxed until most have been vaccinated, I’m not sure if a handful of people being vaccinated will create a false sense of security.
 
ziggy said:
I wonder if after being vaccinated can one still carry and pass on the virus? I’m concerned that as soon as people get vaccinated it will be “yahoo, I don’t have to wear a mask and can get back to normal”. Meanwhile, at least at the beginning, the majority of the country will still be waiting to be vaccinated and susceptible to contacting the virus. Personally I can’t see the rules being relaxed until most have been vaccinated, I’m not sure if a handful of people being vaccinated will create a false sense of security.
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In short, no. If you have been vaccinated, your immune system will mount a response which will prevent the virus from replicating. Your body will not be able to produce enough infectious particles to be able to infect someone else.
 
CBsqrd said:
In short, no. If you have been vaccinated, your immune system will mount a response which will prevent the virus from replicating. Your body will not be able to produce enough infectious particles to be able to infect someone else.
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Someone on CNN asked this question to Dr. Fauci and he said that they simply don't no at this point but the fact that the vaccine will reduce symptoms from being severe/deadly to mild/asymptomatic he will take it any day of the week.
 
Vaccines should start arriving early next week. ~32,000 doses for BC based on a per capita base. More to come. Not clear yet if the will give them out to 32k people and then wait for the next shipment or give them to 17K people and then another shot 2 to 4 weeks later.
 

Canada to receive early delivery of Pfizer-BioNTech COVID-19 vaccine​

From: Public Services and Procurement Canada

News release​

December 7, 2020 - Gatineau, Quebec - Public Services and Procurement Canada
The Government of Canada is delivering on its commitment to ensure that Canadians have access to safe and effective COVID-19 vaccines as soon as possible.
The Honourable Anita Anand, Minister of Public Services and Procurement, announced today that following successful negotiations, Canada will receive up to 249,000 doses of the Pfizer-BioNTech COVID-19 vaccine in December 2020, contingent on Health Canada authorization of the vaccine.
These doses are part of the up to 76 million doses Canada has secured through its existing agreement with Pfizer. As with all COVID-19 vaccine candidates, the Pfizer-BioNTech vaccine must be authorized by Health Canada before being administered to Canadians.
Pfizer, the Public Health Agency of Canada with the Canadian Armed Forces, and the Provinces and Territories are working together to finalize preparations at the first point-of-use sites this week, including training on how to handle the product, which must be transported and stored at -70 degrees Celsius.
Important logistical tests are planned, beginning with a dry run with Pfizer this week, led by the National Operations Centre. This dry run will be used to confirm the ordering, shipping and importation processes from the point of manufacture to the point of use across Canada. In this initial dry run with Pfizer, a shipping container with dry ice and a data-logger will simulate a shipment of the vaccine.
The Government of Canada expects to conduct other rehearsals to confirm ordering and shipping processes for additional vaccines as they become available. These test activities are important to ensure that the Provinces and Territories have the necessary infrastructure and equipment in place and are able to plan to effectively and efficiently administer COVID-19 vaccines as they roll-out.
Pfizer submitted an application for regulatory review of its COVID-19 vaccine candidate under Health Canada’s interim order on October 9, 2020. Results of this review are expected soon.

Quotes​

“The Government of Canada continues to do everything possible to protect Canadians from COVID-19. This includes securing the world’s most extensive portfolio of vaccines and taking all necessary measures to ready the country to receive doses once they are authorized for use.”
The Honourable Anita Anand
Minister of Public Services and Procurement
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“We continue to prepare for distribution with provinces and territories, as experts and scientists of the government of Canada are assessing the safety of COVID-19 vaccine candidates. Canadians can be confident that when a vaccine is ready, Canada will be ready.”
The Honourable Patty Hajdu
Minister of Health
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Quick facts​

  • The Public Health Agency of Canada is working with all levels of industry, government and health agencies to have 14 locations across Canada ready to receive the Pfizer vaccines in December 2020.
  • Up to 249,000 doses of the Pfizer vaccine will arrive in a series of shipments, not all at once.
  • The dry run with Pfizer in December will allow for the validation of logistical processes prior to distribution on a national scale.
  • The Government of Canada has signed agreements with the following companies to secure access to their COVID-19 vaccine candidates:
    • Pfizer, which will supply a minimum of 20 million doses and up to 76 million doses of its messenger RNA (mRNA) vaccine candidate developed with BioNTech, BNT162b2.
    • Medicago, which will supply up to 76 million doses of its virus-like particle vaccine candidate.
    • AstraZeneca, which will supply up to 20 million doses of its viral vector vaccine candidate AZD1222.
    • Sanofi and GlaxoSmithKline, which will supply up to 72 million doses of their protein subunit vaccine candidate.
    • Johnson & Johnson, which will supply up to 38 million doses of its viral vector vaccine candidate Ad26.COV2.S.
    • Novavax, which will supply up to 76 million doses of its protein subunit vaccine candidate NVX-CoV2373.
    • Moderna, which will supply up to 56 million doses of its mRNA vaccine candidate mRNA-1273.
  • All vaccine candidates must go through pre-clinical and clinical trials. Health Canada will continue to review evidence of safety, efficacy, and manufacturing quality for each vaccine candidate as it becomes available to decide whether the product will be approved for use in Canada.
  • At this time, there are no vaccines authorized for the prevention of COVID-19 in Canada.
  • The Government of Canada has purchased 126 freezers to store COVID-19 vaccines, including 26 freezers to store ultra-low temperature vaccines such as the Pfizer vaccine. To date, 9 ultra-low temperature freezers have been delivered.


https://www.canada.ca/en/public-ser...very-of-pfizer-biontech-covid-19-vaccine.html
 
GLG said:
Vaccines should start arriving early next week. ~32,000 doses for BC based on a per capita base. More to come. Not clear yet if the will give them out to 32k people and then wait for the next shipment or give them to 17K people and then another shot 2 to 4 weeks later.
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just saw on the news will be given to same person so about 16,000 people in BC will be vaccinated
 
CBsqrd said:
In short, no. If you have been vaccinated, your immune system will mount a response which will prevent the virus from replicating. Your body will not be able to produce enough infectious particles to be able to infect someone else.
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Hope you’re right but Pfizer seems not so sure.
www.businessinsider.com

Pfizer's chairman says it's not clear whether people who are vaccinated can still spread COVID-19

Albert Bourla told NBC's "Dateline" show that whether the vaccine stops virus transmission is "something that needs to be examined."
www.businessinsider.com www.businessinsider.com
 
"the CDC website clearly states in its COVID-19 information page that:
“Regarding vaccination, we won’t know how long immunity lasts until we have a vaccine and more data on how well it works.”

So we can't say that they might be good for only 2-3 months... maybe it will be permeant. Or for 10 years-- no point in speculating.. just give me what you have got to keep me alive NOW
 
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