If you want to do it "cushy" style, there's Pierre's in Echo bay
http://www.pierresbay.com/
I took the GF there two summers ago-- rented a suite for four days--comfy as can be. Boat moored outside on the dock, lots of good food in the restaurant or cook your own. That photo in my avatar was taken from the porch of the suite---quite a joint
Two things, though. IT is a MAJOR destination for huge puker boats (as in 35 - 60 ft RV's with bow thrusters) I remember the GF commenting one fine morning---"Wow, it's just like staying in an RV Park..." Lots of chatter, martini brouhahas, comings and goings of jolly people (if that's your thing)
The second thing: if you're an avid fisherman (salmon), be prepared to burn gas to get to the good stuff. Maybe cooler dudes then me will chime in to the contrary but I found that area to be a biological desert for salmon. All the action I had was heading in to Echo Bay (Malcom, Flower Island, Cracroft etc, generally the Johnstone Strait area) It seemed the deeper you got into the Broughton Archipelago the skinnier it got for salmon (I'm talking springs; I heard when the coho run it's a bit more entertaining)
For rockfish---different story---huge concentrations of spiny units. The GF loved it---drop a jig, reel in a fish....drop a jig, reel in a fish....and on and on and on. I start yawning after a few of those but she still talks about that trip and "all the fish we got"----money well spent...ha ha
Incredible First Nation ruins to go check out, though. Mamaliliculla is an amazing "ruin"---better go see it quick---the trees and mother nature are taking it back to where it belongs....
good luck